Accepted for Publication: December 7, 2014.
Published Online: February 25, 2015. doi:10.1001/jamadermatol.2014.5391.
Study concept and design: Coleman, Gudjonsson.
Acquisition, analysis, or interpretation of data: All Authors.
Drafting of the manuscript: All authors.
Critical revision of the manuscript for important intellectual content: Coleman, Gudjonsson.
Administrative, technical, or material support: Coleman.
Study supervision: All authors.
Conflict of Interest Disclosures: Dr Stecher reports being employed by and having stock options from XBiotech USA. Dr Gudjonsson reports being a consultant for XBiotech USA. No other disclosures were reported.
Funding/Support: This study was supported in part by Xbiotech USA.
Role of the Funder/Sponsor: XBiotech USA had a role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Trial Registration: clinicaltrials.gov Identifier: NCT01384630