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Notable Notes |

Fashionable Pathology

Deshan F. Sebaratnam, MBBS(Hons)1; Shano Khoury, MBBS2; Patricia M. Lowe, FACD3
[+] Author Affiliations
1Skin and Cancer Foundation Australia, New South Wales, Westmead, Australia
2Department of Dermatology, Westmead Hospital, Westmead, New South Wales, Australia
3Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
JAMA Dermatol. 2015;151(5):548. doi:10.1001/jamadermatol.2014.5205.
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Morphological descriptions of cutaneous lesions lend themselves to comparisons with the world around us, such as the realms of food,1 animals, or plants.2 Over the ages, the dermatology literature has also been draped with descriptive terms that conjure up ideas of style and fashion.

Mycosis fungoides is often described as having a bathing suit distribution, as are the lesions of angiokeratoma corporis diffusum in Fabry disease. Giant congenital melanocytic nevi were called garment nevi, and hypertrichosis lanuginose aquisita has been likened to a downy coat. Coxsackie virus may manifest as papular-purpuric gloves and socks syndrome, and this distribution is also observed in the peripheral neuropathy of patients with diabetes mellitus. The shawl sign and holster sign are well reported in dermatomyositis, and venous ulcers are typically found over the gaiters’ area. The mitten deformity is observed in recessive dystrophic epidermolysis bullosa, and the distribution of lesions in allergic contact dermatitis naturally draws on the culprit garb, such as belt buckle or shoe dermatitis. Cylindromas are also known as turban tumors, chloasma is sometimes called the mask of pregnancy, and patients with keratosis pilaris rouge appear to be wearing blusher. Morphologically, the buttonhole sign is classically observed in neurofibromas and anetoderma, and the boutonnière deformity is seen in advanced rheumatoid arthritis.

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