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Correspondence |

Lymphomatoid Contact Dermatitis to Baby Wipes

Gary Mendese, MD; Angela Beckford, MD, MPH; Marie-France Demierre, MD
Arch Dermatol. 2010;146(8):918-935. doi:10.1001/archdermatol.2010.169.
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Numerous histologic mimickers of mycosis fungoides (MF) have been reported in the literature. Lymphomatoid contact dermatitis (LCD), which presents as treatment-responsive allergic contact dermatitis (ACD) that histologically resembles MF, is another entity appropriately placed in this category. Numerous allergens have been implicated in this rare variant of ACD, but to our knowledge, there have been no reported cases of LCD in reaction to preservatives found in baby wipes.

Orbaneja  JGDiez  LILozano  JLSalazar  LC Lymphomatoid contact dermatitis: a syndrome produced by epicutaneous hypersensitivity with clinical features and a histopathologic picture similar to that of mycosis fungoides. Contact Dermatitis 1976;2 (3) 139- 143
PubMed Link to Article[[XSLOpenURL/10.1111/cod.1976.2.issue-3]]
Calzavara-Pinton  PCapezzera  RZane  C  et al.  Lymphomatoid allergic contact dermatitis from para-phenylenediamine. Contact Dermatitis 2002;47 (3) 173- 174
PubMed Link to Article[[XSLOpenURL/10.1034/j.1600-0536.2002.470308_10.x]]
Conde-Taboada  ARoson  EFernandez-Redondo  VGarcia-Doval  IDe La Torre  CCruces  M Lymphomatoid contact dermatitis induced by gold earrings. Contact Dermatitis 2007;56 (3) 179- 181
PubMed Link to Article[[XSLOpenURL/10.1111/cod.2007.56.issue-3]]
Marlière  VBeylot-Barry  MDoutre  MS  et al.  Lymphomatoid contact dermatitis caused by isopropyl-diphenylenediamine: two cases. J Allergy Clin Immunol 1998;102 (1) 152- 153
PubMed Link to Article[[XSLOpenURL/10.1016/S0091-6749(98)70069-7]]
Wall  LM Lymphomatoid contact dermatitis due to ethylenediamine dihydrochloride. Contact Dermatitis 1982;8 (1) 51- 54
PubMed Link to Article[[XSLOpenURL/10.1111/cod.1982.8.issue-1]]
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Figure 1.

High-power view, demonstrating epidermotropism with atypical lymphocytes and minimal background spongiosis. No eosinophils are seen (hematoxylin-eosin, original magnification ×40).

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Figure 2.

Sharply demarcated erythematous plaque with substantial scaling.

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