We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
skINsight |

The Vasculature of Nonmelanocytic Skin Tumors in Reflectance Confocal Microscopy: Vascular Features of Basal Cell Carcinoma

Verena Ahlgrimm-Siess, MD; Theresa Cao, DO; Margaret Oliviero, ARNP; Rainer Hofmann-Wellenhof, MD; Harold S. Rabinovitz, MD; Alon Scope, MD
Arch Dermatol. 2010;146(3):353-354. doi:10.1001/archdermatol.2009.380.
Text Size: A A A
Published online


Dermoscopy, particularly polarized dermoscopy, has become an important tool for the examination of vascular structures of pigmented and nonpigmented skin lesions. Branching (arborizing) vessels can be found in about 82% of basal cell carcinomas (BCCs).1 Small-diameter branching vessels are usually found in superficial BCCs (91.7%).2 Reflectance confocal microscopy (RCM) is a new noninvasive imaging technique with cellular-level resolution.3 Many of the structures seen on RCM correlate closely to dermoscopic and histopathologic findings.3 The principal features of BCCs on RCM imaging include dark silhouettes surrounded by collagen bundles and tumor islands delineated from the adjacent stroma by a dark cleft. Furthermore, the vasculature pattern has been demonstrated to play an important role in the diagnosis of BCC.4,5 The vessels in BCC that have been described as canalicular are branched and linear and run parallel to the horizontal (en face) plane of RCM imaging. We report 2 cases of BCC demonstrating these vascular features.

Figures in this Article

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

6 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections