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Correspondence |

Combined Multifocal Indeterminate Cell Histiocytosis and Basal Cell Carcinoma

Jamison E. Strahan, MD; Joe A. Chorny, MD; Joel L. Cohen, MD; Mayumi Fujita, MD, PhD
Arch Dermatol. 2010;146(3):346-347. doi:10.1001/archdermatol.2010.13.
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Lau  SKChu  PGWeiss  LM Immunohistochemical expression of langerin in Langerhans cell histiocytosis and non-Langerhans cell histiocytic disorders. Am J Surg Pathol 2008;32 (4) 615- 619
PubMed Link to Article[[XSLOpenURL/10.1097/PAS.0b013e31815b212b]]
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PubMed Link to Article[[XSLOpenURL/10.1097/00000372-199610000-00012]]
Simonart  TUrbain  FVerdebout  JMFeoli  FLespagnard  LDargent  JL Langerhans cell histiocytosis arising at the site of basal cell carcinoma excision. J Cutan Pathol 2000;27 (9) 476- 478
PubMed Link to Article[[XSLOpenURL/10.1034/j.1600-0560.2000.027009476.x]]
Izikson  LVanderpool  JBrodsky  GMihm  MC  JrZembowicz  A Combined basal cell carcinoma and Langerhans cell histiocytosis of the scrotum in a patient with occupational exposure to coal tar and dust. Int J Dermatol 2004;43 (9) 678- 680
PubMed Link to Article[[XSLOpenURL/10.1111/ijd.2004.43.issue-9]]
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PubMed Link to Article[[XSLOpenURL/10.1016/S0190-9622(83)70052-6]]
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Figure 1.

Clinical photograph of the combined indeterminate cell histiocytosis and basal cell carcinoma of the right neck. The scar is from a recent incisional biopsy. Both neoplasms were later completely excised.

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Figure 2.

Photomicrographs of specimens of basal cell carcinoma with indeterminate cell histiocytosis. A and B, Hematoxylin-eosin stain (original magnifications ×40 and ×200, respectively). C, Positive staining for CD1a (3-amino-9-ethylcarbazole [AEC] red stain, original magnification ×100). D, Negative langerin staining (AEC red stain, original magnification ×100) (note the positive staining of the normal epidermal Langerhans cells).

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