Accepted for Publication: January 11, 2014.
Published Online: May 28, 2014. doi:10.1001/jamadermatol.2014.27.
Study concept and design: Jacobs, Liu, Kayser, Nijsten.
Acquisition, analysis, or interpretation of data: Jacobs, Liu, Bleyen, Spector, Kayser, Nijsten.
Drafting of the manuscript: Jacobs, Liu, Bleyen, Gunn, Nijsten.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Jacobs, Liu.
Obtained funding: Gunn, Hofman, Klaver, Uitterlinden, Bataille, Spector, Kayser, Nijsten.
Administrative, technical, or material support: Jacobs, Liu, Kayser, Nijsten.
Study supervision: Liu, Hofman, Klaver, Uitterlinden, Neumann, Bataille, Spector, Kayser, Nijsten.
Conflict of Interest Disclosures: None reported.
Funding/Support: This study was supported in part by grants 175.010.2005.011 and 911-03-012 from the Netherlands Organization of Scientific Research Investments, by grants 014-93-015 and RIDE2 from the Research Institute for Diseases in the Elderly, by the Netherlands Genomics Initiative, and by the Netherlands Consortium for Healthy Ageing.
Role of the Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: Jacobus Hagoort, MA (Erasmus Medical Center), critically reviewed the manuscript. We thank the participants and data collectors of the Rotterdam Study and the TwinsUK.