Accepted for Publication: December 11, 2013.
Published Online: May 21, 2014. doi:10.1001/jamadermatol.2013.10368.
Study concept and design: Wee, Mortimer, Holden.
Acquisition of data: Wee, Lindhurst, Chong, Biesecker.
Analysis and interpretation of data: Wee, Lindhurst, Biesecker.
Drafting of the manuscript: Wee, Chong, Biesecker.
Critical revision of the manuscript for important intellectual content: Wee, Mortimer, Lindhurst, Holden.
Obtained funding: Biesecker.
Administrative, technical, and material support: Lindhurst, Chong, Biesecker.
Study supervision: Mortimer, Biesecker, Holden.
Conflict of Interest Disclosures: Drs Lindhurst and Biesecker receive royalties from Genentech Corp for development of Proteus patient cell lines. Dr Biesecker receives honoraria from Wiley-Blackwell for editorial duties, which has no relationship to this article. No other disclosures are reported.
Funding/Support: This article was supported in part by the National Institutes of Health. Drs Lindhurst and Biesecker are funded by the Intramural Research Program of the National Human Genome Research Institute.
Role of the Sponsor: The National Institutes of Health had no role in the design and conduct of the study; collection, management, analysis, or interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: Hadley Bloomhardt, BSc, National Human Genome Research Institute, performed the molecular assays. She was not compensated for her contribution.