Accepted for Publication: December 6, 2013.
Published Online: May 14, 2014. doi:10.1001/jamadermatol.2013.10225.
Study concept and design: Chen, Rajadhyaksha.
Acquisition of data: Chen, Sierra, Cordova, Rajadhyaksha.
Analysis and interpretation of data: Chen, Sierra, Cordova, Rajadhyaksha.
Drafting of the manuscript: Chen.
Critical revision of the manuscript for important intellectual content: Chen, Sierra, Cordova, Rajadhyaksha.
Obtained funding: Rajadhyaksha.
Administrative, technical, or material support: Chen, Sierra, Cordova, Rajadhyaksha.
Study supervision: Chen, Rajadhyaksha.
Conflict of Interest Disclosures: Dr Rajadhyaksha is a former employee of and owns equity in Caliber Imaging and Diagnostics Inc (formerly, Lucid Inc), the company that makes and sells the VivaScope confocal scanning laser microscope. The VivaScope is the commercial version of an original laboratory prototype that was developed by Dr Rajadhyaksha when he was in the Department of Dermatology at Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Funding/Support: This study was partially supported by National Institutes of Health (NIH) grant R01EB012466 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) Image-Guided Interventions program.
Role of the Sponsor: The NIH and NIBIB had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: We are undebted to Steven Wilson, BS, and Reza Afzalneia, MS, Memorial Sloan Kettering Skin Cancer Center, for preparing the histology sections, and Kivanc Kose, PhD, Dermatology Service, Memorial Sloan Kettering Cancer Center, for technical support in preparing the figures. None of these acknowledged persons received compensation for their contributions.