Accepted for Publication: November 13, 2013.
Published Online: April 16, 2014. doi:10.1001/jamadermatol.2013.9715.
Study concept and design: All authors.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Hurley.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Hurley.
Study supervision: Lane.
Conflict of Interest Disclosures: Dr Stafford reports past expert testimony for Mylan Pharmaceuticals, a manufacturer of generic medications, regarding patterns of doxycycline use in the treatment of rosacea. No other disclosures were reported.
Funding/Support: Dr Stafford’s contribution to this study was supported in part by midcareer mentoring award K24-HL086703 from the National Heart, Lung, and Blood Institute. The Stanford Translational Research Integrated Database Environment (STRIDE) project was supported by grant UL1 RR025744 from the National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health.
Role of the Sponsor: The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Disclaimer: The statements, findings, conclusions, views, and opinions contained and expressed in this article are based in part on data obtained under license from the following IMS Health Incorporated information service: National Disease and Therapeutic Index (1997-2009), IMS Health Incorporated. The statements, findings, conclusions, views, and opinions contained and expressed herein are neither representative of the official views of the National Institutes of Health nor necessarily those of IMS Health Incorporated or any of its affiliated or subsidiary entities.
Previous Presentation: This study was previously published as an abstract and presented as a poster at the 72nd Annual Meeting of the Society for Investigative Dermatology; May 10, 2012; Raleigh, North Carolina; and at the 38th Annual Meeting of the Society for Pediatric Dermatology; July 12, 2012; Monterey, California.
Additional Contributions: David Peng, MD, MPH (Department of Dermatology, Keck School of Medicine of USC, University of Southern California, Los Angeles) and Jean Tang, MD (Department of Dermatology, Stanford University School of Medicine) critically reviewed the manuscript, and Raymond R. Balise, PhD (Department of Health Research and Policy, Stanford University School of Medicine) provided valuable guidance. We thank the Stanford Center for Clinical Informatics and the STRIDE project.