Large primary cutaneous melanomas convey an ominous risk of metastases. The finding of large-scale melanomas without regional or distant metastases suggests a less aggressive biology for this type of tumor.
Article InformationCorresponding Author: Daniela Kroshinsky, MD, MPH, Harvard Medical School, Massachusetts General Hospital, 50 Staniford St, Ste 200, Boston, MA 02114 (firstname.lastname@example.org).
Published Online: January 29, 2014. doi:10.1001/jamadermatol.2013.6892.
Conflict of Interest Disclosures: None reported.
Additional Contributions: We are indebted to Greg Sakamoto, MD, for his help with the diagnosis and management of these interesting cases.