JAMA Dermatology Clinicopathological Challenge |

Elusive Diagnosis of Left Ear Nodules

Shinko Koko Lin, MD1,2; Mark Philip Guralnick, MD1,2,3; David Samuel Cassarino, MD, PhD1,2
[+] Author Affiliations
1Department of Dermatology, Sunset Medical Center, Southern California Kaiser Permanente, Los Angeles
2Department of Pathology, Sunset Medical Center, Southern California Kaiser Permanente, Los Angeles
3Woodland Hills Medical Center, Woodland Hills, California
JAMA Dermatol. 2014;150(1):81-82. doi:10.1001/jamadermatol.2013.5371.
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A, Clinical photograph of the left ear showing multiple pink agminated papules and nodules. B, Histologic section showing numerous large nodular collections of enlarged, foamy-appearing histiocytes demonstrating exuberant emperipolesis of numerous inflammatory cells, including lymphocytes, plasma cells, and neutrophils (hematoxylin-eosin, original magnification ×400). C, S100 immunohistochemical stain showing strong staining of histiocytes (original magnification ×200).

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