Case Report/Case Series | The cutting Edge

Topical Timolol for Recalcitrant Wounds

Liza R. Braun, BA1; Sonia A. Lamel, MD1; Nicholas A. Richmond, BS1; Robert S. Kirsner, MD, PhD1
[+] Author Affiliations
1Department of Dermatology and Cutaneous Surgery, University of Miami, Miller School of Medicine, Miami, Florida
JAMA Dermatol. 2013;149(12):1400-1402. doi:10.1001/jamadermatol.2013.7135.
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Braun and coauthors describe patients treated with timolol for recalcitrant wounds.

Section Editor: Edward W. Cowen, MD, MHSc; Assistant Section Editors: Murad Alam, MD; Ruth Ann Vleugels, MD.

Article Information

Accepted for Publication: July 23, 2013.

Corresponding Author: Robert S. Kirsner, MD, PhD, Department of Dermatology and Cutaneous Surgery, University of Miami, Miller School of Medicine, 1600 NW 10th Ave, Rosenstiel Medical Sciences Building, Room 2023-A, Miami, FL 33136.

Published Online: October 30, 2013. doi:10.1001/jamadermatol.2013.7135.

Author Contributions: Dr Kirsner and Ms Braun had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Study concept and design: Braun, Richmond, Kirsner.

Acquisition of data: Braun, Richmond, Kirsner.

Analysis and interpretation of data: Braun, Lamel, Kirsner.

Drafting of the manuscript: Braun, Lamel, Richmond.

Critical revision of the manuscript for important intellectual content: All authors.

Statistical analysis: Braun, Richmond.

Administrative, technical, or material support: Braun, Kirsner.

Study supervision: Kirsner.

Conflict of Interest Disclosures: None reported.

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Figure 1.
Patient 2 Before Epithelialization

A 1.0-cm2 chronic wound from patient 2, resulting from venous insufficiency, on the dorsum of the right foot before administration of topical timolol, 0.5%.

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Figure 2.
Patient 2 After Epithelialization

Complete reepithelialization of a chronic wound from patient 2 after 7 weeks of weekly topical timolol, 0.5%, treatment with standard of care.

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