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Comment & Response |

Efficacy of Topical Antifungal Agents in the Treatment of Dermatophytosis—Reply

Inajara Rotta, MSc1; Cassyano Januário Correr, PhD2
[+] Author Affiliations
1Pharmaceutical Sciences Postgraduate Program, Federal University of Parana, Curitiba, Brazil
2Department of Pharmacy, Federal University of Parana, Curitiba, Brazil
JAMA Dermatol. 2013;149(10):1244. doi:10.1001/jamadermatol.2013.5064.
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In Reply Our systematic review and mixed-treatment comparison meta-analysis showed no significant differences among 14 topical antifungal agents for mycologic cure.1 We also have found that butenafine, naftifine, and terbinafine might be the best treatments for maintaining a cure in patients with dermatophytosis.1 German language randomized clinical trials were not included in our review, which is 1 limitation of the study. Nevertheless, we believe that even if these studies were included, our results would not have changed significantly.

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October 1, 2013
Zbys Fedorowicz, MSc, DPH; Esther J van Zuuren, MD
1UK Cochrane Centre (Bahrain Branch), The Cochrane Collaboration, Awali, Bahrain
2Department of Dermatology, Leiden University Medical Centre, 2300 RC Leiden, the Netherlands
JAMA Dermatol. 2013;149(10):1243-1244. doi:10.1001/jamadermatol.2013.5065.
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