0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comment & Response |

Efficacy of Topical Antifungal Agents in the Treatment of Dermatophytosis: An Incomplete Meta-Analysis

Zbys Fedorowicz, MSc, DPH1; Esther J van Zuuren, MD2
[+] Author Affiliations
1UK Cochrane Centre (Bahrain Branch), The Cochrane Collaboration, Awali, Bahrain
2Department of Dermatology, Leiden University Medical Centre, 2300 RC Leiden, the Netherlands
JAMA Dermatol. 2013;149(10):1243-1244. doi:10.1001/jamadermatol.2013.5065.
Text Size: A A A
Published online

Extract

To the Editor The authors are to be congratulated for conducting this important but challenging systematic review.1 However, while accepting its degree of complexity, we are at variance with the confidence expressed by the authors in the strengths of their study, including a thorough search of the literature and exclusion of lower-quality reports assessed using the Jadad score.

A thorough literature search is a key requirement of a high-quality systematic review and, as the authors confirm, should show all the evidence available at the time of the study.1 Although their search appeared comprehensive, language of publication was clearly a restriction; ie, only studies in English, Spanish, and Portuguese were included. The exclusion of studies based on language of publication is a significant source of bias, which has been well documented, and in this review, the language restriction excludes studies published in the German language.2,3 Hand searching of pre-1987 issues of Mykosen would have identified additional eligible trials, most of which are written in German, and which, based on the flowchart included as the first figure in the article, would have represented a not insignificant percentage of the total number of included trials. The review excluded a number of German studies equivalent to the number of Spanish and Portuguese studies that were included, clearly illustrating the impact of language bias and the not inconsequential gap in the evidence included in this systematic review.

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

October 1, 2013
Inajara Rotta, MSc; Cassyano Januário Correr, PhD
1Pharmaceutical Sciences Postgraduate Program, Federal University of Parana, Curitiba, Brazil
2Department of Pharmacy, Federal University of Parana, Curitiba, Brazil
JAMA Dermatol. 2013;149(10):1244. doi:10.1001/jamadermatol.2013.5064.
CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Related Collections
Jobs
brightcove.createExperiences();