Accepted for Publication: June 27, 2013.
Published Online: October 9, 2013. doi:10.1001/jamadermatol.2013.6440.
Study concept and design: D. Hexsel.
Acquisition of data: All authors.
Analysis and interpretation of data: D. Hexsel, Siega, Rotta, Rodrigues.
Drafting of the manuscript: D. Hexsel, Siega, Schilling-Souza, Rodrigues.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Siega, Rodrigues.
Administrative, technical, and material support: D. Hexsel, C. Hexsel, Rotta, Rodrigues.
Study supervision: D. Hexsel, Siega, Schilling-Souza, Rodrigues.
Conflict of Interest Disclosures: Dr D Hexsel has received research funding from L’Óreal, Cynosure, Syneron, Ipsen, Allergan, Galderma, and Medicis; has served as a consultant for Ipsen and Galderma; and has been a member of the speakers bureaus for Ipsen and Galderma. No other disclosures were reported.
Funding/Support: This study was supported by the Brazilian Center for Studies in Dermatology, a nonprofit organization.
Role of the Sponsors: This was a nonsponsored study. The Brazilian Center for Studies in Dermatology designed and conducted the study; collected, analyzed, and interpreted the data; and prepared, reviewed, and approved the manuscript
Additional Contributions: Andy Pickett, PhD, provided critical commentaries on this article, for which he received no financial compensation. Diana Monti Atik, BPharm, an employee of the research center during the trial, assisted with acquisition of the data and received her usual salary support.