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Successful Treatment of Perianal Giant Condyloma Acuminatum in an Immunocompromised Host With Systemic Interleukin 2 and Topical Cidofovir

Vinod E. Nambudiri, MD, MBA1; Kudakwashe Mutyambizi, MD, MPhil1; Andrew C. Walls, BSc1; David C. Fisher, MD2; Ronald Bleday, MD2,3; Arturo P. Saavedra, MD, PhD, MBA1,2
[+] Author Affiliations
1Department of Dermatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
2Dana Farber Cancer Institute, Boston, Massachusetts
3Division of Colorectal Surgery, Department of Surgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
JAMA Dermatol. 2013;149(9):1068-1070. doi:10.1001/jamadermatol.2013.5160.
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Section Editor: Edward W. Cowen, MD, MHSc; Assistant Section Editors: Murad Alam, MD; Ruth Ann Vleugels, MD

Article Information

Accepted for Publication: May 7, 2013.

Corresponding Author: Arturo P. Saavedra, MD, PhD, MBA, Department of Dermatology, Brigham and Women’s Hospital, Harvard Medical School, 221 Longwood Ave, Boston, MA 02115 (asoavedra@partners.org).

Published Online: July 3, 2013. doi:10.1001/jamadermatol.2013.5160.

Author Contributions: All authors had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Study concept and design: Fisher, Bleday, Saavedra.

Acquisition of data: Fisher, Bleday, Saavedra.

Analysis and interpretation of data: All authors.

Drafting of the manuscript: All authors.

Critical revision of the manuscript for important intellectual content: All authors.

Administrative, technical, and material support: All authors.

Study supervision: Saavedra.

Conflict of Interest Disclosures: None reported.

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Figure 1.
Patient Photograph at Time of Physical Examination

Circumferential, exophytic, friable perianal mass consistent with giant anal condyloma.

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Figure 2.
Photograph 16 Months After Treatment Initiation

Sixteen months after surgical debulking and interleukin 2 and topical cidofovir therapies, 2 small recurrent papules occurred at 10-o’clock position.

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