We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Editorial |

Psoriasis and the Obesity Epidemic The Effect of Weight Loss

Michael T. Caglia, MD1; Gerald G. Krueger, MD1
[+] Author Affiliations
1Department of Dermatology, University of Utah, Salt Lake City
JAMA Dermatol. 2013;149(7):786-787. doi:10.1001/jamadermatol.2013.4512.
Text Size: A A A
Published online


Man’s desire to control chronic disease inevitably turns to how diet could affect the disease state; we would purport that this notion is likely related to the common wisdom “you are what you eat.” Since even before the now widely appreciated association between obesity and psoriasis, the effect of weight loss on the management of psoriasis has been under consideration. Soon after World War II, Simons1 reported observations of 13 subjects with psoriasis who were imprisoned in Japanese starvation camps in Java. He noted that weight loss and disease severity were inconsistent in these persons. The more recent associations of psoriasis and obesity—increased risk of onset of psoriasis, more of the body surface affected with disease, increased risk of psoriatic arthritis (PsA), and increased cardiovascular risk—establish that obesity has a very negative impact on psoriasis.2,3 Furthermore, these associations are strongly supported by the often dramatic response of psoriasis and PsA to treatment with agents that target tumor necrosis factor (TNF) and the fact that TNF has a strong association with obesity: levels of TNF increase and decrease, respectively, with weight gain and weight loss.4

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

1 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Collections

Promoción de la salud en el ciclo de vida