Correspondence |

Foreign-Body Reaction to Wound Seal

Laura J. Lester, MD; Aaron K. Joseph, MD
JAMA Dermatol. 2013;149(5):632. doi:10.1001/jamadermatol.2013.2620.
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Wound Seal (Biolife LLC) is a product composed of a hydrophilic polymer and potassium iron oxyacid salt that aids in hemostasis in wounds that are left to heal by secondary intention. We report a foreign-body reaction that results in the dermis following its use.

Correspondence: Dr Lester, University of Texas Medical School at Houston, 6655 Travis St, Ste 980, Houston, TX 77030 (laura.j.lester@gmail.com).

Conflict of Interest Disclosures: None reported.

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Figure 1. Frozen tissue specimen showing dermal scar and granulomatous infiltrate surrounding geometric, basophilic foreign-body particles (hematoxylin-eosin, original magnification ×4).

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Figure 2. Frozen tissue specimen (hematoxylin-eosin, original magnification ×10). This specimen shows a granulomatous infiltrate with multinucleated giant cells surrounding geometric, basophilic particles of varying size and shape and smaller golden-brown particles.




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