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Correspondence |

The Use of Aprepitant in Brachioradial Pruritus

Mina S. Ally, BSc, MBBS; Christina S. Gamba, BA; David H. Peng, MD; Jean Y. Tang, MD, PhD
JAMA Dermatol. 2013;149(5):627-628. doi:10.1001/jamadermatol.2013.170.
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Brachioradial pruritus (BRP) is characterized by intractable itching localized to the dorsolateral aspects of the arms.1,2 Aprepitant (Emend; Merck & Co Inc), approved in 2003 for chemotherapy-induced nausea and vomiting, has been used successfully to treat patients with chronic pruritus,3,4 but to our knowledge, its use in BRP has not yet been reported.

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Figure 1. Linear excoriations, angular erosions, and crusted, erythematous papules and nodules over the dorsolateral aspect of the right forearm and hand prior to treatment with aprepitant.

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Figure 2. At 6-week follow-up, the excoriated papules and erosions appear significantly improved.

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The use of aprepitant in brachioradial pruritus. JAMA Dermatol 2013;149(5):627-8.
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