Research Letter |

Effects of a Chemical Sunscreen on UV-Induced Changes of Different Histological Features in Melanocytic Nevi

Cesare Massone, MD1; Peter Wolf, MD1,2; Stephan Gringschl, MD1; H. Peter Soyer, MD3; Rainer Hofmann-Wellenhof, MD1
[+] Author Affiliations
1Department of Dermatology, Medical University of Graz, Graz, Austria
2Research Unit for Photodermatology, Medical University of Graz, Graz
3Dermatology Research Centre, The University of Queensland, School of Medicine, Princess Alexandra Hospital, Brisbane, Australia
JAMA Dermatol. 2013;149(7):874-875. doi:10.1001/jamadermatol.2013.420.
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Several studies have investigated the effect of UV radiation on melanocytic nevi by using different approaches and different sources and types of irradiation.1 We read with interest the work of Carrera et al,2 and we would like to describe our experience also.3

Article Information

Accepted for Publication: December 12, 2012.

Corresponding Author: Dr Hofmann-Wellenhof, Department of Dermatology, Medical University of Graz, Auenbruggerplatz 8, A-8036 Graz, Austria (rainer.hofmann@medunigraz.at).

Author Contributions: All authors had full access to all of the data in the study and take the responsibility for the integrity of the data and the accuracy of the data analysis.

Study concept and design: Massone, Wolf, Soyer, and Hofmann-Wellenhof.

Acquisition of data: Wolf, Gringschl, and Hofmann-Wellenhof.

Analysis and interpretation of data: Massone, Wolf, Gringschl, and Soyer.

Drafting of the manuscript: Massone.

Critical revision of the manuscript for important intellectual content: Wolf, Soyer, and Hofmann-Wellenhof.

Statistical analysis: Wolf and Hofmann-Wellenhof.

Administrative, technical, and material support: Massone, Wolf, Gringschl, and Soyer.

Study supervision: Wolf, Soyer, and Hofmann-Wellenhof.

Published Online: May 8, 2013. doi:10.1001/jamadermatol.2013.420.

Conflict of Interest Disclosures: None reported.

Funding/Support: This project was supported by an unrestricted research grant from Beiersdorf AG, Hamburg, Germany.

Additional Contributions: We thank Volker Wendel and Heiner Gers-Barlag, Beiersdorf AG, Hamburg, Germany, for their help and support in determining the emission spectra of the solar simulator radiation equipment.

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HMB-45 Antibodies Stain

The HMB-45 antibodies stain was significantly stronger in the unprotected half (right side, dark blue margin) compared with the protected half.

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