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Correspondence |

Merkel Cell Carcinoma: Complete Clinical Remission Associated With Disease Progression

Antoine Bertolotti, MD; Helene Conte, MD; Louis François, MD; Caroline Dutriaux, MD; Khaled Ezzedine, PhD; Pierre Mélard, MD; Béatrice Vergier, PhD; Alain Taieb, PhD; Thomas Jouary, MD
JAMA Dermatol. 2013;149(4):501-502. doi:10.1001/jamadermatol.2013.2596.
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Clinical regression is well known in Merkel cell carcinoma (MCC). We report herein a particular case of clinical regression of a primary MCC associated with regional disease progression.

Correspondence: Dr Jouary, Unité de Dermatologie-Cancérologie, Service de Dermatologie, Hôpital Saint André, 1, rue Jean Burguet, 33075 Bordeaux CEDEX, France (thomas.jouary@chu-bordeaux.fr).

Conflict of Interest Disclosures: None reported.

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Figure 1. Clinical images (A and B) and positron-emission tomography (PET) scans (C and D) from the subject case. A, Large Merkel cell carcinoma on the tip of the nose. B, One month later, complete clinical regression of the tumor. C and D, Hypermetabolic cervical lymph nodes on PET imaging.

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Figure 2. Immunohistochemical studies with anti-CD4 staining (A) and anti-CD8 staining (B) (original magnification ×10 for both).

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