Lupus pernio is a specific sarcoidosis skin lesion characterized by violaceous indurated plaques primarily affecting the central face. It is a hallmark of chronic disease, and treatment remains challenging because conventional therapies often fail.
Correspondence: Dr Dalm, Department of Immunology, Erasmus Medical Center, Gravendijkwal 230, 3015 CE Rotterdam, the Netherlands (email@example.com).
Conflict of Interest Disclosures: None reported.
Funding/Support: The lenalidomide was provided for our patient by Celgene Corporation without charge; the drug is not registered in the Netherlands for the treatment of sarcoidosis and so its use in this context is not covered by health insurance.
Role of the Sponsor: Celgene Corporation had no role in the design and conduct of the study; in the collection, analysis and interpretation of the data; or in the preparation, review, or approval of the manuscript.