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Correspondence |

Indomethacin for Refractory Infantile Eosinophilic Pustular Folliculitis

Ellen Toyonaga, MD; Riichiro Abe, MD, PhD; Reine Moriuchi, MD; Kei Ito, MD, PhD; Yukiko Abe, MD, PhD; Hiroshi Shimizu, MD, PhD
JAMA Dermatol. 2013;149(3):367-368. doi:10.1001/2013.jamadermatol.591.
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Eosinophilic pustular folliculitis (EPF) in infancy is a rare disease. In infantile EPF, the lesions tend to resolve spontaneously or to respond well to topical corticosteroid treatment. We present herein a case of infantile EPF that was resistant to topical corticosteroid but showed great improvement after administration of oral indomethacin.

Author Affiliations: Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

Correspondence: Dr R. Abe, Department of Dermatology, Hokkaido University Graduate School of Medicine, North 15, West 7, Kita-ku, Sapporo 060-8638, Japan.

Conflict of Interest Disclosures: None reported.

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Figure 1. Vesicles, pustules, and crusted lesions are seen on the palm (A) and sole (B).

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Figure 2. Hematoxylin-eosin–stained punch biopsy specimens of the sole show subcorneal pustules containing eosinophils and neutrophils. Original magnifications ×40 (A) and ×400 (B).

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