Importance Hidradenitis suppurativa (HS) is a chronic debilitating cutaneous disease for which there is no universally effective treatment. Patients typically present at puberty with tender subcutaneous nodules that can progress to dermal abscess formation. Antiandrogens have been used in the treatment of HS, and studies have primarily focused on adult patients.
Observations We present a case series of 3 pediatric patients with HS who were successfully treated with oral finasteride, resulting in decreased frequency and severity of disease flares with no significant adverse effects.
Conclusions and Relevance Finasteride is a therapeutic option that provides benefit for pediatric patients with HS. Further prospective data and randomized controlled studies will provide helpful information in the management of this disease.
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Figure 1. At initial presentation, patient 3 had multiple inflammatory erythematous nodules on both inner thighs.
Figure 2. Patient 3 had tender erythematous nodules in the perianal region at presentation.
Figure 3. After 3 years of finasteride therapy, patient 3 showed significant resolution of active disease, with a decrease in inflammatory nodules and residual scarring and dyspigmentation on the inner thighs.
Figure 4. Patient 3 had residual scarring and dyspigmentation in the perianal area after 3 years of finasteride therapy.
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