0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Correspondence |

Worsening of Bullous Pemphigoid Following Bacillus Calmette-Guérin Treatment for Bladder Cancer

Jamie L. Johnson, BS; Daniel A. West, MD; Jeffrey B. Travers, MD, PhD
JAMA Dermatol. 2013;149(2):248-249. doi:10.1001/2013.jamadermatol.729.
Text Size: A A A
Published online

Extract

Bullous pemphigoid is an autoimmune disease characterized by subepidermal bullae that can involve nearly any skin surface and primarily affects the elderly. Only in a minority of cases are there known precipitating factors, some of which include vaccinations.1

Report of a Case.  An 86-year-old white man with a 5-year history of bullous pemphigoid presented with a flare of disease activity. Until this flare, his disease had been well controlled for approximately 1 year, and he was blister free under treatment with mycophenolate mofetil, 500 mg/d, prednisone, 5 mg/d, and doxycycline, 100 mg/d. He was recently diagnosed as having bladder cancer and began intravesical bacillus Calmette-Guérin (BCG) treatments. New blister development began approximately 1 week after initiating therapy. By the end of the second week, he was experiencing a significant flare and declined further BCG treatment. His prednisone dose was increased to 20 mg/d, and his symptoms rapidly improved by his clinic visit.

Figures in this Article

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Place holder to copy figure label and caption
Graphic Jump Location

Figure. Exacerbation of bullous pemphigoid following bacillus Calmette-Guérin treatments approximately 1 week after prednisone dose was increased.

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
Jobs
brightcove.createExperiences();