Accepted for Publication: August 2, 2012.
Author Contributions: All authors had full access to the data in this report and take responsibility for its integrity and the accuracy of the analysis. Study concept and design: Hausauer, Parvataneni, and Chren. Acquisition of data: Hausauer, Parvataneni, Stuart, and Chren. Analysis and interpretation of data: Hausauer, Maurer, Leslie, Parvataneni, and Chren. Drafting of the manuscript: Hausauer, Maurer, Leslie, Parvataneni, and Chren. Critical revision of the manuscript for important intellectual content: Hausauer, Maurer, Leslie, Stuart, and Chren. Statistical analysis: Hausauer, Parvataneni, and Chren. Obtained funding: Chren. Administrative, technical, and material support: Hausauer, Leslie, and Stuart. Study supervision: Hausauer, Maurer, and Chren.
Conflict of Interest Disclosures: Dr Chren is a consultant for Genentech Inc.
Funding/Support: This work was supported by grants R01 AR 054983 and K24 AR052667 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health.