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Research Letters | Jan 2013

Quality of Life Differences Between Responders and Nonresponders in the Treatment of Cutaneous Lupus Erythematosus

Aileen Y. Chang, MD; Elizabeth Ghazi, MD; Joyce Okawa, RN; Victoria P. Werth, MD

JAMA Dermatol. 2013;149(1):104-106. doi:10.1001/2013.jamadermatol.467.

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Patients with cutaneous lupus erythematosus (CLE) have very poor quality of life.¹ When compared with those with other skin diseases, patients with CLE are among those most severely affected by their condition. Psychologic aspects of quality of life in CLE are similar to, or worse than, what is experienced by patients with chronic hypertension, congestive heart failure, type 2 diabetes mellitus, and recent myocardial infarction. In considering this, we were interested in assessing whether patients who demonstrated response to treatment also experienced change to their quality of life.

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Figure. Skindex-29³ subscale scores for responders (A) and nonresponders (B). Illustrated are Emotions, Functioning, and Symptoms subscale scores obtained before and after treatment (Tx). Blue lines indicate mean score. Black lines connect data from before and after Tx for the same individual.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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Chang AY, Ghazi E, Okawa J, Werth VP. Quality of Life Differences Between Responders and Nonresponders in the Treatment of Cutaneous Lupus Erythematosus. JAMA Dermatol. 2013;149(1):104-106. doi:10.1001/2013.jamadermatol.467.

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