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Correspondence |

Stevens-Johnson Syndrome Without Skin Lesions (Fuchs Syndrome): A Literature Review of Adult Cases With Mycoplasma Cause

Kayi Li, MD, BHSc; Richard M. Haber, MD, FRCPC
Arch Dermatol. 2012;148(8):963-964. doi:10.1001/archdermatol.2012.681.
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The characteristics of Stevens-Johnson syndrome (SJS) include a generalized cutaneous eruption, fever, inflamed buccal mucosa, and severe purulent conjunctivitis.1 Stevens-Johnson syndrome without skin lesions and only mucosal involvement has been described as Fuchs syndrome in Germany and is believed to be a variant of erythema multiforme majus.2 This presentation is also known as atypical SJS and Mycoplasma pneumoniae –associated mucositis when caused by a Mycoplasma infection.2 Fuchs syndrome associated with Mycoplasma pneumoniae has usually been seen in children and adolescents. To our knowledge, only 7 cases in the adult population have been reported.

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Figure. Crusting on the upper and lower lips in a patient with Fuchs syndrome.




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Erythema multiforme. Am Fam Physician 1992;46(4):1171-6.