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Evidence-Based Dermatology: Research Commentary | Aug 2012

The Relationship Between Hygiene and Microbial Burden in Atopic Dermatitis Risk Based on a Systematic Review

Meghan Dickman, MD; Annelise L. Dawson, MD; Robert P. Dellavalle, MD, PhD, MSPH

Arch Dermatol. 2012;148(8):936-938. doi:10.1001/archdermatol.2012.1410.

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Commentary on: Atopic dermatitis and the hygiene hypothesis revisited
Flohr C, Yeo L
Curr Probl Dermatol. 2011;41:1-34

Question: Is there evidence to support an association between atopic dermatitis (AD) and hygiene as it relates to microbial burden? Does the literature support a link between any particular infectious or anti-infectious (ie, antibiotics, vaccinations) agent and AD?

Data Sources: A systematic review of the literature was performed using studies identified via a MEDLINE search from 1966 until June 2010. Search findings were supplemented by a hand search of references contained within studies located by MEDLINE search. 49 new studies were deemed suitable for inclusion.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

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Dickman M, Dawson AL, Dellavalle RP. The Relationship Between Hygiene and Microbial Burden in Atopic Dermatitis Risk Based on a Systematic Review. Arch Dermatol. 2012;148(8):936-938. doi:10.1001/archdermatol.2012.1410.

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