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Research Letters |

Quantifying the Orientation of Acquired Melanocytic Nevi on the Back

Phil McClenahan, BSc; Tristan Blake, BPharmaceutSc, MPharm; Nicola Douglas, BSc, MBChB; Stephen Gilmore, MBBS; H. Peter Soyer, MD, FACD
Arch Dermatol. 2012;148(7):857-859. doi:10.1001/archdermatol.2012.494.
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Acquired melanocytic nevi are a well-known risk factor in the development of melanoma; their increased frequency is associated with increased risk. Many recent studies have focused on the dermoscopic diagnosis of melanoma in addition to investigation of nevogenesis.12 However, the clinical appearance of nevus orientation has not been a target of investigation. Although not aiming to identify new phenomena, we attempt herein to quantify and explain the orientation patterns of acquired melanocytic nevi on the back. Blaschko lines are a well-described pattern of skin lines that correlates with epidermal nevi and may relate to acquired melanocytic nevus orientation.3 Quatresooz et al,4 while investigating lines of tension in skin on the back, identified a dermoscopic parallel melanotic line pattern on the normal skin of the back aligned with skin tension lines called Langer lines.4 We propose that a pattern of acquired melanocytic nevus orientation is identifiable and may be associated with both Blaschko and Langer lines.

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Figures

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Grahic Jump Location

Figure 1. Cropped patient image used for recording nevus orientation between the base of the neck and the natal cleft. Dimensions are 1500 × 2500 pixels.

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Figure 2. Measurement of nevus angle. A, Left of midline, the angle is measured from the vertical in an anticlockwise direction. B, Right of midline, the angle is measured from the vertical in a clockwise direction.

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Grahic Jump Location

Figure 3. Individual nevus angle is shown to be dependent on vertical position on the back. Individual nevi are represented by the black dots. The curving trend line indicates a predictive model relating nevus angle to vertical position on the back following the quadratic equation y = −213.3 x2 + 162.3 x + 121.4.

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Grahic Jump Location

Figure 4. Composite patient data plot and line association. A, All recorded lesions drawn at corresponding coordinates, size, and orientation. B, Langer lines of the back, adapted from Langer.5 C, Overlay of lesion data plot and Langer lines.

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