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The Cutting Edge: Challenges in Medical and Surgical Therapies | May 2012

Subcutaneous Interferon Alfa for the Treatment of Cutaneous Pseudolymphoma

Holly Leigh Singletary, MD; M. Angelica Selim, MD; Elise Olsen, MD

Arch Dermatol. 2012;148(5):572-574. doi:10.1001/archdermatol.2011.1016.

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Herein we report a case of recalcitrant cutaneous pseudolymphoma (CPL) treated with subcutaneous interferon.

Correspondence: Elise Olsen, MD, Department of Dermatology, Duke University Medical Center, PO Box 3294, Durham, NC 27710 (olsen001@mc.duke.edu).

Accepted for Publication: August 21, 2011.

Author Contributions: All authors had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Singletary and Olsen. Acquisition of data: Singletary, Selim, and Olsen. Analysis and interpretation of data: Singletary, Selim, and Olsen. Drafting of the manuscript: Singletary and Olsen. Critical revision of the manuscript for important intellectual content: Singletary, Selim, and Olsen. Obtained funding: Olsen. Administrative, technical, or material support: Singletary and Olsen. Study supervision: Olsen.

Financial Disclosure: None reported.

Funding/Support: This study was supported in part by the Duke Cutaneous Lymphoma and Research Treatment Center.

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Figure 2. Dense, monomorphic perivascular and interstitial lymphocytic dermal infiltrate (hematoxylin-eosin, original magnification ×40).

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Figure 3. Complete clearance of skin lesions 3 months after starting subcuticular injections of interferon alfa-2b.

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Singletary H, Selim M, Olsen E. Subcutaneous Interferon Alfa for the Treatment of Cutaneous Pseudolymphoma. Arch Dermatol. 2012;148(5):572-574. doi:10.1001/archdermatol.2011.1016.

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