Raynaud syndrome is a vasospastic disorder of the fingers, toes, and other body sites often associated with exposure to cold temperatures or emotional stress.1- 3 Although responses to pharmacologic therapies are helpful, some cases are recalcitrant, leading to persistent pain and ulceration.
Correspondence: Andrew G. Franks Jr, MD, The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, Tisch H-100, 550 First Ave, New York, NY 10016 (Andrew.Franks@nyumc.org).
Accepted for Publication: August 18, 2011.
Author Contributions: All authors had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Smith, Polsky, and Franks. Acquisition of data: Smith and Franks. Analysis and interpretation of data: Smith, Polsky, and Franks. Drafting of the manuscript: Smith and Franks. Critical revision of the manuscript for important intellectual content: Smith, Polsky, and Franks. Administrative, technical, and material support: Smith, Polsky, and Franks. Study supervision: Polsky and Franks.
Financial Disclosure: None reported.
Additional Contributions: We thank Carolina Kowalczyk, BA, for preparation and technical assistance with the manuscript. Bruce Stroeber, MD, PhD, Aieska DeSouza, MD, and Angela Hu, BA, were the statisticians.