Accepted for Publication: January 31, 2011.
Published Online: April 11, 2011. doi:10.1001/archdermatol.2011.84
Author Contributions: Drs Senet, Vicaut, and Chosidow had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Senet, Vicaut, Debure, Lok, and Chosidow. Acquisition of data: Senet, Vicaut, Beneton, Debure, Lok, and Chosidow. Analysis and interpretation of data: Senet, Vicaut, Debure, and Chosidow. Drafting of the manuscript: Senet, Vicaut, and Chosidow. Critical revision of the manuscript for important intellectual content: Senet, Vicaut, Beneton, Debure, Lok, and Chosidow. Statistical analysis: Vicaut, and Chosidow. Obtained funding: Senet, Vicaut, and Chosidow. Administrative, technical, and material support: Senet, Vicaut, Beneton, Debure, Lok, and Chosidow. Study supervision: Senet, Vicaut, and Chosidow.
Financial Disclosure: Dr Chosidow received consulting fees from Johnson & Johnson that did not concern wound care products.
Funding/Support: This study was supported in part by AP-HP, the French Society of Dermatology, and the AFSSAPS (Agence Fran çaise de S écurit é Sanitaire des Produits de Sant é). Johnson & Johnson France provided the becaplermin gel (Regranex Gel).
Role of the Sponsors: The sponsors had no role in the design and conduct of the study; in the collection, analysis, and interpretation of data; or in the preparation, review, or approval of the manuscript.
Additional Contributions: We are indebted to the investigators, members of the French Angio-Dermatology Group of the French Society of Dermatology (Nathalie Baudot, MD, Edouard Begon, MD, Christophe Bedanne, MD, PhD, Jean-Marie M. Bonnet Blanc, MD, PhD, Guillaume Chaby, MD, Jacqueline Chevrant Breton, MD, PhD, Olivier Dereure, MD, PhD, Vincent Descamps, MD, PhD, S égol ène Fays-Bouchon, MD, Juliette Fontaine, MD, Philippe Humbert, MD, PhD, Isabelle Kupfer, MD, PhD, Laurence Lecleach, MD, Philippe Modiano, MD, PhD, Saskia Oro, MD, Barbara Roth, MD, Fran çois Truchetet, MD); and to AP-HP personnel for their inestimable technical support (Fabien Maugard and Saliha Djane, MD, from the Direction de la Recherche Clinique; Sophie Gerard, Mounir Aout, and Veronique Jouis from the Unit é de Recherche Clinique; Brigitte Lehman from the Agence G én érale des Equipements et Produits de Sant é).