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Correspondence |

Senna-Containing Laxative Inducing Blistering Dermatitis in Toddlers

Wallace A. Smith, BS; Adam R. Taintor, MD; Liborka Kos, MD; Beth Drolet, MD
Arch Dermatol. 2012;148(3):402-404. doi:10.1001/archdermatol.2011.2750.
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Correspondence: Dr Kos, Department of Dermatology, Medical College of Wisconsin, 9200 W Wisconsin Ave, Milwaukee, WI 53226 (lkos@childrenspg.org).

Financial Disclosure: None reported.

Food and Drug Administration, HHS. Laxative drug products for over-the-counter human use: final rule. Fed Regist. 1999;64(19):4535-4540
PubMed
Morales MA, Hern ández D, Bustamante S, Bachiller I, Rojas A.Is senna laxative use associated to cathartic colon, genotoxicity, or carcinogenicity? [published online September 15, 2009]. J Toxicol. 2009;2009287247
PubMed  |  Link to Article
Leventhal JM, Griffin D, Duncan KO, Starling S, Christian CW, Kutz T.Laxative-induced dermatitis of the buttocks incorrectly suspected to Be abusive burns. Pediatrics. 2001;107(1):178-179
PubMed   |  Link to Article[[XSLOpenURL/10.1542/peds.107.1.178]]
Spiller HA, Winter ML, Weber JA, Krenzelok EP, Anderson DL, Ryan ML.Skin breakdown and blisters from senna-containing laxatives in young children. Ann Pharmacother. 2003;37(5):636-639
PubMed   |  Link to Article[[XSLOpenURL/10.1345/aph.1C439]]
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Grahic Jump Location

Figure 1. A well-demarcated, diamond-shaped erosion with desquamation involving the lower scrotum, perineum, and buttocks.

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Grahic Jump Location

Figure 2. A well-demarcated, diamond-shaped erosion with bullae.

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