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Correspondence |

Aquagenic Urticaria and Syncope Associated With Occult Papillary Thyroid Carcinoma and Improvement After Total Thyroidectomy

Esen Özkaya, MD; Meryem Sevin ç Elin ç-Aslan, MD; Sezen Yazici, MD
Arch Dermatol. 2011;147(12):1461-1462. doi:10.1001/archderm.147.12.1461.
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Correspondence: Dr Özkaya, Department of Dermatology, Istanbul University, 34093 Istanbul, Turkey (profeo@istanbul.edu.tr).

Financial Disclosure: None reported.

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Figure 1. Clinical images of the forearm. A, Positive challenge tests with hot (40 °C), ice-cold, and room-temperature water on the forearm within 20 minutes. B, Bicarbonated water (500 g/50 L) immersion test led to pruritic and burning edematous plaque within 2 hours.

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Figure 2. Delayed onset of pruritic erythema on the trunk (A), upper extremities (B), and lower extremities (C). Reactions occurred 2 hours after a 5-minute bath with bicarbonated water during combined therapy with oral antihistamines and narrowband UV-B. Attacks of syncope could be prevented by combined intervention.




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