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Correspondence | Oct 2011

Acquired Smooth Muscle Hamartoma of the Patchy Follicular Variant With Meyerson Phenomenon

Mitsuhiro Matsuda, MD; Takahiro Hamada, MD; Norito Ishii, MD; Yasuhiko Maeyama, MD; Takekuni Nakama, MD; Shinichiro Yasumoto, MD; Takashi Hashimoto, MD

Arch Dermatol. 2011;147(10):1234-1235. doi:10.1001/archdermatol.2011.294.

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Smooth muscle hamartoma (SMH) is an organoid malformation characterized by a painless hyperpigmented plaque with local hypertrichosis that is generally found on the trunk or proximal limbs, with lesions ranging from 2 to 10 cm in diameter. Histological examination reveals an increased density of smooth muscle bundles in the dermis and subcutis. Herein, we describe a Japanese patient with acquired SMH with Meyerson phenomenon. Histologically, a lymphoeosinophilic infiltrate in the dermis coexisted with the features of SMH.

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Figure 1. Dark brown plaque with follicular papulation was present on the right upper arm. The faint erythema developed on the inner half of the lesion.

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Figure 2. A skin biopsy specimen. A, An increased number of circumscribed bundles of smooth muscle fibers (hematoxylin-eosin, original magnification ×40). B, Lymphoeosinophilic infiltrate around smooth muscle bundles (hematoxylin-eosin, original magnification ×200).

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Matsuda M, Hamada T, Ishii N, et al. Acquired Smooth Muscle Hamartoma of the Patchy Follicular Variant With Meyerson Phenomenon. Arch Dermatol. 2011;147(10):1234-1235. doi:10.1001/archdermatol.2011.294.

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