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Correspondence |

Genital Erythrodysesthesia as a Severe Manifestation of Capecitabine Therapy: A Report of 3 Cases

Beatriz Fleta-As ín, MD; Javier Alc ántara-Gonz ález, MD; Leticia Alonso-Castro, MD; Mayte Truchuelo-D íez, MD; Pedro Ja én-Olasolo, PhD
Arch Dermatol. 2011;147(9):1123-1124. doi:10.1001/archdermatol.2011.257.
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Capecitabine is an oral chemotherapeutic agent derived from fluorouracil. Hand-foot syndrome (HFS) is a characteristic skin toxic effect responsible in some cases for drug treatment discontinuation; genital involvement has rarely been reported. Recently, we observed scrotal involvement in 3 patients treated with capecitabine.

Correspondence: Dr Fleta-As ín, Dermatology Department, Ram ón y Cajal hospital, Carretera de Colmenar Viejo, km 9,100, 28034 Madrid, Spain (beatriz.fleta.trabajo@gmail.com).

Financial Disclosure: None reported.

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Figure. Scrotal diffuse erythema and yellowish crusts.




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