Accepted for Publication: April 13, 2011.
Author Contributions : Drs Nakajima and Kabashima had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Watanabe, Sugita, Hashimoto, Tokura, Miyachi, and Kabashima. Acquisition of data: Nakajima, Tohyama, Iijima, Nishimura, Doi, and Tanioka. Analysis and interpretation of data: Nakajima, Watanabe, Hashimoto, and Kabashima. Drafting of the manuscript: Nakajima, Watanabe, Tohyama, Sugita, Hashimoto, Tokura, Nishimura, Doi, Miyachi, and Kabashima. Critical revision of the manuscript for important intellectual content: Nakajima, Iijima, Tanioka, Miyachi, and Kabashima. Obtained funding: Tanioka and Kabashima. Administrative, technical, and material support: Nakajima, Watanabe, Tohyama, Sugita, Hashimoto, Nishimura, Doi, and Miyachi. Study supervision: Iijima, Hashimoto, Tokura, and Kabashima.
Financial Disclosure: None reported.
Funding/Support: This work was supported in part by Grants-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology, and Health and Labor Sciences Research Grants (Research on Intractable Diseases) from the Ministry of Health, Labor, and Welfare of Japan.