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Correspondence |

Lymphomatoid Drug Reaction to Ustekinumab

Jae Jung, MD; Ethan Charles Levin, MD; Robert Jarrett, MD; Dongsi Lu, MD; Caroline Mann, MD
Arch Dermatol. 2011;147(8):992-993. doi:10.1001/archdermatol.2011.213.
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Correspondence: Dr Mann, 660 S Euclid, Box 8123, St Louis, MO 63110 (CMANN@dom.wustl.edu).

Financial Disclosure: None reported.

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Figure 1. Asymptomatic, indurated pink papules and nodules on the back.

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Figure 2. Biopsy specimens from our patient. A, Histopathologic findings include nodular aggregates of lymphocytes (hematoxylin-eosin, original magnification ×10). Lymphocytic aggregates were mostly CD3+ T cells (B) (CD3 immunostain, original magnification ×20) with some larger atypical CD30+ T cells (C) (CD30 immunostain, original magnification ×40). The absence of sheetlike architecture of the CD30+ cells is consistent with a reactive process.




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