Accepted for Publication: August 18, 2011.
Published Online: November 21, 2011. doi:10.1001/archdermatol.2011.356
Author Contributions: Drs Harris and Leachman had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Harris and Leachman. Acquisition of data: Harris, Florell, Papenfuss, Jahromi, Kohlmann, Schiffman, Quackenbush, Cassidy, and Leachman. Analysis and interpretation of data: Harris, Florell, Jahromi, Schiffman, Quackenbush, Cassidy, and Leachman. Drafting of the manuscript: Harris, Florell, Jahromi, Schiffman, Quackenbush, and Leachman. Critical revision of the manuscript for important intellectual content: Harris, Florell, Jahromi, Papenfuss, Kohlmann, Schiffman, Quackenbush, Cassidy, and Leachman. Obtained funding: Leachman. Administrative, technical, and material support: Harris, Florell, Papenfuss, Schiffman, Cassidy, and Leachman. Study supervision: Florell and Leachman.
Financial Disclosure: None reported.
Funding/Support: This study was supported in part by GeneDx (ExonArray CGH performance). The majority of funding for the study was through the Tom C. Mathews Familial Melanoma Research Clinic Endowment, the Huntsman Cancer Foundation, and Institutional Core support through Genetic Counseling Core (Huntsman Cancer Institute Cancer Center Support Grant P30CA042014).
Additional Contributions: We wish to thank Kristina Heintz, RN, BSN, for her clinical coordination with the patient; Brad V. Graham, BS, MS, for technical support with BRAF sequencing; and Sherri Bale, PhD, and her team at GeneDx, Gaithersburg, Maryland, for performing the ExonArrayDx analysis.