Accepted for Publication: June 7, 2011.
Author Contributions: All authors had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Abraham, West, and Lacouture. Acquisition of data: Borovicka, Calahan, Gandhi, Abraham, and Lacouture. Analysis and interpretation of data: Borovicka, Calahan, Kwasny, Haley, and Lacouture. Drafting of the manuscript: Borovicka. Critical revision of the manuscript for important intellectual content: Calahan, Gandhi, Abraham, Kwasny, Haley, West, and Lacouture. Statistical analysis: Kwasny. Administrative, technical, or material support: Borovicka, Calahan, Gandhi, Abraham, Haley, West, and Lacouture. Study supervision: Lacouture.
Financial Disclosure: Dr West serves as a paid consultant to Sage Products Inc and has also served as a consultant or received honoraria from Shionogi Pharma. Dr Lacouture serves as a consultant or receives honoraria from OSI Pharmaceuticals Inc, Bristol-Myers Squibb, ImClone Systems Inc, Eli Lilly & Co, Bayer HealthCare Pharmaceuticals Inc, Onyx Pharmaceuticals Inc, GlaxoSmithKline, Amgen Inc, Pfizer, Vertex Pharmaceuticals, and Vivus. The Department of Dermatology at Northwestern University has received or is currently receiving research grants from Abbott Labs, Skin of Color Society, Medicis Pharmaceutical Corp, Yaupon Therapeutics, Biogen, NuGene, Basilea Pharmaceutica, RegeneRx, Johnson & Johnson, Galderma, 3M, Allergan, Lindi Skin, Hana Biosciences, Regeneron, Celgene, American Society for Dermatologic Surgery, IPC Pharma, Astellas, Alwyn, Leo Pharma, National Institutes of Health, Shape Pharmaceuticals, Northgate Technologies Inc, OSI Pharmaceuticals Inc, Centocor Ortho Biotech Inc, Genentech, Bayer, Amgen, Pierre Fabre Pharmaceuticals, GlaxoSmithKline, Bristol-Myers Squibb, Pfizer, Onyx Pharmaceuticals, Novartis, and ImClone Systems Inc.
Funding/Support: This study was supported in part by a Zell Scholarship from the Robert H. Lurie Comprehensive Cancer Center (Dr Lacouture) and by a Dermatology Foundation Career Development Award (Dr Lacouture).
Role of the Sponsors: The sponsors had no role in the design and conduct of the study; in the collection, analysis, and interpretation of data; or in the preparation, review, or approval of the manuscript.
Previous Presentations: This study was read in part at the Annual Meeting of the American Academy of Dermatology; March 7, 2010; Miami, Florida; and displayed as a scientific poster at the Annual Meeting of the American Society of Clinical Oncology; June 4-8, 2010; Chicago, Illinois; the Multinational Association of Supportive Care in Cancer 2010 International Symposium; June 24-26, 2010; Vancouver, British Columbia, Canada; and the Ninth International Kidney Cancer Symposium; October 1-2, 2010; Chicago, Illinois.